Arthritis in children affects around one in a thousand children. In the majority of cases the cause is unknown. It is likely that the development of arthritis is related in part to the child's genetic make-up and in part to other factors such as infection or other illnesses. The arthritis may go away after some months or years or may persist into adult life. At the moment we cannot predict which children will recover and which children will have more long-term problems.
Better understanding of the cause of childhood arthritis may lead to the possibility of prevention of the illness in future. Better understanding of the course of the illness will help in choosing the best treatment for children in the future.
What is the purpose of the study?
To describe, in children/adolescents with arthritis, both the short and long term outcomes, including;
1. Physical (joint inflammation/damage, disability, growth, pain)
2. Quality of life (education, leisure/sports activities, psychological impact)
3. Treatment Response/side effects
4. Progression into adulthood
CAPS was initially set up as a pilot study and ethical approval for the full study was given on 18th February 2003. CAPS recruitment target is 2000+ patients and all participants enrolled in the study will be followed for 10 years and at the ages of 16, 18 and 21.
When did the study start?
What is the study for?
The aim of the study is to identify factors that may be involved in the development of arthritis and to identify factors that may help in the prediction of the long- term outcome of the illness. Also, to identify genetic and environmental predictors of outcome of arthritis in children including;